There was one incident the place a 44 year previous woman who had been taking 3000 mg of lysine per day for 5 years developed Franconi's syndrome, which manifested as tubulo-intersistial nephritis. However, carbohydrate rich meals will be excessive in energy due to the fillings and toppings commonly added to them - similar to creamy sauces on pasta and butter or cheese on baked potatoes.

KMTs catalyze mono-, di-, or tri-methylation by transfering one, two, or three methyl groups, respectively, from S-adenosyl-L-methionine to the ε-amino group of a lysine residue.

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